chondrocytes

[Science Advances] Scientists examined the necessity of the ERAD complex in chondrocytes for cartilage formation and maintenance.

[Science Translational Medicine] Scientists demonstrated that a biodegradable piezoelectric poly(L-lactic acid) nanofiber scaffold under applied force or joint load could act as a battery-less electrical stimulator to promote chondrogenesis and cartilage regeneration.

[Tissue Engineering Part C-Methods] Investigators examined whether integration of allogeneic cell-based implants with the surrounding native cartilage could be demonstrated in an ex vivo human osteochondral culture model.

[Advanced Healthcare Materials] A platelet lysate-rich plasma macroporous hydrogel scaffold with around 100 μm pore size and 1.25 MPa Young's modulus was developed to sustainedly recruit and polarize endogenous anti-inflammatory macrophages for improving cartilage defect repair.

[Nature Communications] In Ppara−/− mice, the authors found that an increased DNL stimulated the cartilage degradation and identified ACOT12 as a key regulatory factor.

[Scientific Reports] Researchers compared human fibronectin adhesion assay-derived chondroprogenitors with migratory chondroprogenitors in normoxic and hypoxic culture conditions, investigating their growth characteristics, surface marker profile and trilineage potency.