Tag results:
chronic inflammation
Immune Regulation News
Putative Regulation of Macrophage-Mediated Inflammation by Catestatin
[Trends in Immunology] Investigators hypothesize that macrophages produce catestatin in an inflammation-dependent manner and thereby might self-regulate inflammation in an autocrine fashion.
Hepatic Cell News
Association between Immunologic Markers and Cirrhosis in Individuals with Chronic Hepatitis B
[Scientific Reports] The authors sampled 175 hepatocellular carcinoma, 117 cirrhotic and 165 non-cirrhotic controls from a prospective cohort study of chronically hepatitis B virus-infected individuals to assess immunologic markers in relation to liver disease.
Hematopoiesis News
Signal-Transducing Adaptor Protein-1 and -2 in Hematopoiesis and Diseases
[Experimental Hematology] Recent findings have shown the critical roles of signal-transducing adaptor protein (STAP)-2 in B cell progenitor cells in marrow under hematopoietic stress and STAP-1 and -2 in BCR-ABL-transduced leukemogenesis. In this review, the authors focus on the role of STAPs in the bone marrow.
Dermal Cell News
NAMPT-Derived NAD+ Fuels PARP1 to Promote Skin Inflammation through Parthanatos Cell Death
[PLoS Biology] Investigators reported that the genetic and pharmacological inhibition of nicotinamide phosphoribosyltransferase (Nampt), the rate-limiting enzyme in the salvage pathway of NAD+ biosynthesis, reduced oxidative stress and cell death in zebrafish models of chronic skin inflammation.
Immune Regulation News
RvD1 Accelerates the Resolution of Inflammation by Promoting Apoptosis of the Recruited Macrophages via the ALX/FasL-FasR/Caspase-3 Signaling Pathway
[Cell Death Discovery] Mice were administered Resolvin D1 via the tail vein 3 and 4 days after stimulation with lipopolysaccharide.
Muscle Cell News
Resolvin-D2 Targets Myogenic Cells and Improves Muscle Regeneration in Duchenne Muscular Dystrophy
[Nature Communications] Resolvin-D2 directly targeted myogenic cells and promoted their differentiation and the expansion of the pool of myogenic progenitor cells leading to increased myogenesis.