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circulating tumor cells

The Double Agents in Liquid Biopsy: Promoter and Informant Biomarkers of Early Metastases in Breast Cancer

[Molecular Cancer] Investigators discuss in detail the divergence of early metastases as circulating tumor cells (CTCs) and the involvement of microRNAs (miRNAs) as detectable blood-based diagnostic biomarkers that warrant a timely screening of cancer, serial monitoring of therapeutic response, and the dynamic molecular adaptations induced by miRNAs on CTCs.

Overexpression of Multiple Epidermal Growth Factor Like Domains 11 Rescues Anoikis Survival through Tumor Cells-Platelet Interaction in Triple Negative Breast Cancer Cells

[Life Sciences] The role of multiple epidermal growth factor like domains 11 (MEGF11) was studied in human TNBC MDA-MB-231 and MDA-MB-468 cells by overexpressing MEGF11 using non-attached culture.

The Double Agents in Liquid Biopsy: Promoter and Informant Biomarkers of Early Metastases in Breast Cancer

[Molecular Cancer] Scientists discuss in detail the divergence of early metastases as circulating tumor cells and the involvement of miRNAs as detectable blood-based diagnostic biomarkers that warrant a timely screening of cancer.

Rapid and Highly Sensitive Approach for Multiplexed Somatic Fusion Detection

[Modern Pathology] Researchers identified fusions from as little as two unstained slides of FFPE tumor biopsy tissue, from circulating tumor cells collected from tumor-bearing mice, and from liquid biopsy samples from patients with known fusion-positive cancers.

Dynamic Detection of HER2 of Circulating Tumor Cells in Patients with Gastric Carcinoma and Its Clinical Application

[Molecular Medicine Reports] Investigators constructed and characterized human epidermal growth factor receptor 2 (HER2) lipid magnetic ball for separating circulating tumor cells in patients with gastric carcinoma.

Application of Surface-Enhanced Raman Spectroscopy to Guide Therapy for Advanced Prostate Cancer Patients

[ACS Sensors] Investigators demonstrated a linear calibration curve from cell lysate and correlate lysate protein with mRNA from cultured prostate cancer cells.

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