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clinical trial

LianBio Announces First Patient Dosed in Registrational Phase 3 EXPLORER-CN Trial of Mavacamten in Chinese Patients with Obstructive Hypertrophic Cardiomyopathy

[LianBio, Inc.] LianBio, Inc. announced the first patient has been dosed in the Phase III EXPLORER-CN clinical trial of mavacamten in Chinese patients with symptomatic obstructive hypertrophic cardiomyopathy.

Accutar Biotechnology Announces FDA Clearance of IND Application for Phase I Trial of AC0176 in Prostate Cancer

[Accutar Biotechnology, Inc.] Accutar Biotechnology, Inc. announced that the US FDA has cleared the company’s investigational new drug application (IND) for AC0176 for the treatment of patients with metastatic CRPC.

NOXXON Provides Progress Update on the Expansion Arms of the Phase I/II GLORIA Trial with NOX-A12 in Brain Cancer Patients

[NOXXON Pharma N.V.] NOXXON Pharma N.V. announced that the Data Safety Monitoring Board positively evaluated safety data from the initial four weeks of treatment of the first patient enrolled in the GLORIA clinical trial expansion arm.

Longeveron Announces Initiation of Phase IIa Clinical Trial of Lomecel-B for the Treatment of Alzheimer’s Disease

[Longeveron, Inc.] Longeveron, Inc. announced the initiation of its Phase IIa clinical trial evaluating Lomecel-B as a treatment for Alzheimer’s disease (AD). The Phase IIa trial is designed to measure brain anatomy using MRI, and include detailed assessments of the inflammatory and vascular systems thought to contribute to the worsening of AD.

Researchers Awarded Grant to Study New Method of Islet Transplantation

[Weill Cornell Medicine] Weill Cornell Medicine researchers have received a two-year $500,000 grant from JDRF to evaluate an innovative approach to islet cell transplantation, an experimental treatment for difficult-to-control type 1 diabetes.

High Efficacy and Safety of CD38 and BCMA Bispecific CAR-T in Relapsed or Refractory Multiple Myeloma

[Journal of Experimental & Clinical Cancer Research] The authors assessed the efficacy and safety of B cell maturation antigen (BCMA) and CD38 bispecific CAR-T cells in refractory multiple myeloma patients.

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