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clinical trial

MRM Health Announces First Patient Dosed with Next Generation Live Microbiome Consortia Therapeutic MH002 in Phase Ib/IIa Study in Patients with Ulcerative Colitis

[MRM Health] MRM Health announced that the first patient received MH002 in a Phase Ib/IIa multi-center clinical trial in mild-to-moderate ulcerative colitis.

SOTIO Announces Clinical Collaboration with MSD to Evaluate IL-15 Superagonist, SOT101, in Combination with KEYTRUDA® (Pembrolizumab) in Patients with Solid Tumors

[SOTIO Biotech] SOTIO Biotech announced that it has entered into a clinical trial collaboration and supply agreement with MSD to evaluate the combination of SOT101, SOTIO’s IL-15 superagonist, and MSD’s KEYTRUDA® in patients with selected advanced/refractory solid tumors in the Phase II AURELIO-04 study.

NOXXON Announces Enrollment of First Patient in the Expansion of the NOX-A12 Phase I/II Trial in Brain Cancer

[NOXXON Pharma N.V.] NOXXON Pharma N.V. announced that the first patient was enrolled in an expansion arm of the GLORIA clinical trial of NOX-A12 in MGMT unmethylated brain cancer.

QSAM Biosciences Activates Clinical Sites and Opens Enrollment for Its Phase I Clinical Trial of CycloSam® for the Treatment of Bone Cancer

[QSAM Biosciences, Inc.] QSAM Biosciences, Inc. announced the activation of its first clinical trial site and the initiation of enrollment of patients into its Phase I clinical trial evaluating CycloSam® for multiple types of bone cancer that either originated in or has metastasized to the bone.

Revisiting Fibrosis in Inflammatory Bowel Disease: The Gut Thickens

[Nature Reviews Gastroenterology & Hepatology] Scentists present the state of the art on the most recently identified pathogenic mechanisms of this serious inflammatory bowel disease-related complication, focusing on possible targets of antifibrotic therapies, management strategies, and factors that might predict fibrosis progression or response to treatment.

PDS Biotech Provides Recruitment update for National Cancer Institute-Led Phase 2 Clinical Trial of PDS0101-Based Combination

[PDS Biotechnology Corporation] PDS Biotechnology Corporation announced the reopening of recruitment in the National Cancer Institute-led Phase II clinical trial evaluating PDS0101 in combination with two investigational immune-modulating agents in advanced HPV cancers.

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