Tag results:
clinical trial
Immune Regulation News
Carbon Ion Radiotherapy Triggers Immunogenic Cell Death and Sensitizes Melanoma to Anti-PD-1 Therapy in Mice
[Oncoimmunology] Scientists used human U2OS osteosarcoma cells for the in vitro assessment of immunogenic cell death and established several in vivo models of melanoma in mice.
Extracellular Matrix News
Surface Oncology Achieves $30 Million Milestone with First Patient Dosed in GlaxoSmithKline Phase I Study
[Surface Oncology] Surface Oncology, a clinical-stage immuno-oncology company developing next-generation immunotherapies that target the tumor microenvironment, announced the first patient has been dosed by GlaxoSmithKline in the Phase I study of GSK4381562 in patients with solid tumors.
Neural Cell News
FDA Clears ReAlta Life Science’s Phase II STAR Trial of RLS-0071 in Neonates with Hypoxic-Ischemic Encephalopathy
[ReAlta Life Sciences, Inc.] ReAlta Life Sciences, Inc. announced FDA clearance of an investigational new drug application for a Phase II clinical trial of RLS-0071 in neonates with hypoxic-ischemic encephalopathy.
Mesenchymal Cell News
Stem Cell Biotech Neuroplast Enrolls First Patient in Phase II Clinical Trial of Transformative Neuro-Cells® Treatment for Traumatic Spinal Cord Injury
[Neuroplast] Neuroplast has enrolled its first patient in a Phase II clinical trial to evaluate efficacy of its transformative Neuro-Cells® treatment that aims to prevent further damage to the central nervous system after sustaining acute traumatic spinal cord injury.
Human Immunology News
Regulation of the Antigen Presentation Machinery in Cancer and Its Implication for Immune Surveillance
[Biochemical Society Transactions] Investigators provide a comprehensive overview of physiologically conserved or novel mechanisms utilized by tumor cells to reduce MHC-I or MHC-II expression.
Hepatic Cell News
Neoadjuvant Approaches in Hepatocellular Carcinoma: There’s No Time Like the Present
[Clinical Cancer Research] Investigators appraise the existing literature and current clinical trial landscape of neoadjuvant therapies in HCC.