colorectal cancer cells

[Scientific Reports] Using MRI, scientists determined the correlation between glutamine uptake and the distribution of glutamine transporters, namely ASCT2 and SLC38A2, glutaminase, and CSC markers, such as CD44 and CD166, in a mouse xenograft model of HT29 human colorectal cancer cells.

[Cell Death Discovery] In functional in vitro experiments, researchers observed that calmodulin-binding transcription activator 1 (Camta1) overexpression significantly decreased the proliferation and invasion capacity of SW620 and SW480 cells.

[Cell Death & Disease] Scientists detected the receptor tyrosine kinase activity in gefitinib-resistant colorectal cancer cells, pan-erb-b2 receptor tyrosine kinase 3 (ErbB3)/EGFR was significantly activated and provided a potential multi-ErbB treatment target.

[Translational Oncology] Researchers performed a label-free proteomic analysis of exosomes from a pair of homologous human colorectal cancer cell line with different metastatic abilities.

[Biochimica Et Biophysica Acta-Molecular Cell Research] Scientists showed that ANO1 channel protein was upregulated in human colorectal cancer tissue samples and its upregulation was correlated with the TNM staging, histological type, pathological differentiation and poor prognosis.

[Scientific Reports] Researchers investigated induced pluripotent stem DCs-in vitro transcriptional RNA (ivtRNA) which were induced by transfecting ivtRNA obtained from tumors of three colorectal cancer patients, and examined its antitumor effect.