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colorectal cancer cells

Silencing ESRP1 Expression Promotes Caspase-Independent Cell Death via Nuclear Translocation of AIF in Colon Cancer Cells

[Cellular Signalling] Scientists analyzed Clinical Proteomic Tumor Analysis Consortium, colon tissue microarray, and colon cancer cells to evaluate the ESRP1 expression levels in colorectal cancer subtypes.

Anemoside B4 Sensitizes Human Colorectal Cancer to Fluorouracil-Based Chemotherapy through Src-Mediated Cell Apoptosis

[Aging] Scientists explored the efficacy of anemoside B4 (AB4) in 5-Fluorouracil (FU)-based chemotherapy in colorectal cancer cells and the underlying molecular mechanisms. They indicated a significant synergistic activity of AB4 in 5-FU treated colorectal cancer cells

MICAL1 Inhibits Colorectal Cancer Cell Migration and Proliferation by Regulating the EGR1/β-Catenin Signaling Pathway

[Biochemical Pharmacology] MICAL1 has been reported to be involved in the malignant processes of several types of cancer cells, however, the roles of MICAL1 in colorectal cancer (CRC) have not been well-characterized. Researchers investigated the cellular functions and molecular mechanisms of MICAL1 in CRCs.

Combination of Resveratrol and BIBR1532 Inhibits Proliferation of Colon Cancer Cells by Repressing Expression of LncRNAs

[Medical Oncology] Scientists investigated the effect of resveratrol and BIBR1532, either alone or in combination, on the cell viability as well as on expression of long non-coding RNAs for HT-29 colon adenocarcinoma cells.

Ring Finger 220 Promotes the Stemness and Progression of Colon Cancer Cells via Ubiquitin Specific Peptidase 22-BMI1 Axis

[Bioengineered] Investigators found that RNF220 was upregulated in colorectal cancer in patients and cell models. RT-PCR assay was used to compare differences between expression levels of RNF220 in colorectal tumor and normal tissues.

Musarin, a Novel Protein with Tyrosine Kinase Inhibitory Activity from Trametes versicolor, Accepted Inhibits Colorectal Cancer Stem Cell Growth

[Biomedicine & Pharmacotherapy] Researchers characterized a novel 12-kDa protein that named musarin, which was purified from Trametes versicolor mushroom extract and showed significant growth inhibition on multiple human colorectal cancer cell lines in vitro.

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