colorectal cancer cells

[Oncogene] B-Myb overexpression accelerated cell proliferation, cell cycle progression and cell motility in colorectal cancer cells, and promoted tumor growth in orthotopic nude mouse models in vivo.

[International Reviews of Immunology] The authors explain how different metabolites of tryptophan are involved in the pathophysiology of inflammatory bowel disease (IBD) and colorectal cancer, as a major complication of IBD.

[Cell Death & Disease] Colorectal cancer cells hijacked prostaglandin E2 (PGE2) to non-canonically promote Hedgehog transcriptional factor Gli activity and Gli-dependent proliferation of colorectal cancer cells in a Smo-independent manner.

[Biomarkers in Medicine] Scientists characterized cetuximab and panitumumab exposure influence on miR expression in colorectal cancer cells to identify those regulating the EGFR pathway and implicated in resistance to treatment.

[Oncogene] The authors described the role of the long non-coding RNA SPRY4 intronic transcript 1 (SPRY4-IT1) in cancer metastasis by mechanisms related to Staufen1-mediated mRNA decay, and found that high SPRY4-IT1 expression was associated with aggressiveness and poor outcome in human colorectal, breast and ovarian cancer tissues.

[Nutrition and Cancer-An International Journal] Scientists evaluated the effects of Bryophytes like Abietinella abietina, Homolothecium sericeum, Tortella tortuosa, Syntrichia ruralis, and Bryoerythrophyllum rubrum species extracted with ethyl alcohol on 5-fluorouracil resistant colorectal cancer cell lines.