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COVID-19

Wuhan Market Was Epicentre of Pandemic’s Start, Studies Suggest

[Nature News] Report authors say that the coronavirus SARS-CoV-2 jumped to people from animals sold at the market on two occasions in late 2019 — but some scientists want more definitive evidence.

What Do We Currently Know About Chronic Myeloid Leukemia (CML) and COVID-19?

[Current Oncology Reports] The role of tyrosine kinase inhibitors as protective factors against SARS-CoV-2 infection in patients with CML should be confirmed by large-scale epidemiologic studies.

Virios Therapeutics Announces Research Collaboration Exploring the Potential of Combination Antiviral Therapy for Treating Long COVID

[Virios Therapeutics, Inc.] Virios Therapeutics, Inc. announced a collaboration with the Bateman Horne Center of Salt Lake City to explore the role of combination antiviral therapy in Long COVID, otherwise known as Post-Acute Sequelae of COVID-19.

A Human Pluripotent Stem Cell-Based Model of SARS-CoV-2 Infection Reveals an ACE2-Independent Inflammatory Activation of Vascular Endothelial Cells through TLR4

[Stem Cell Reports] The authors findings supported a direct role for SARS-CoV-2 in mediating endothelial inflammation in an ACE2-dependent or -independent manner.

Tacrolimus-Resistant SARS-CoV-2-Specific T Cell Products to Prevent and Treat Severe COVID-19 in Immunosuppressed Patients

[Molecular Therapy-Methods & Clinical Development] Scientists proposed adoptive transfer of SARS-CoV-2-specific T cells made resistant to a common immunosuppressant, Tacrolimus, for optimized performance in the immunosuppressed patient.

Durable and Deepening Clinical Responses Observed in Post-Treatment Period of Evelo Bioscience’s Phase II Clinical Trial of Oral EDP1815 in Psoriasis

[Evelo Biosciences, Inc.] Evelo Biosciences, Inc. announced data from the post-treatment follow-up of its Phase II trial of EDP1815 in mild and moderate psoriasis including durable and deeper clinical responses.

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