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COVID-19

Live Attenuated Virus Vaccine Protects against SARS-CoV-2 Variants of Concern B.1.1.7 (Alpha) and B.1.351 (Beta)

[Science Advances] Researchers assessed the immunogenicity and protective efficacy of sCPD9 in the Roborovski dwarf hamster, a nontransgenic rodent species that was highly susceptible to SARS-CoV-2 and severe COVID-19–like disease.

Lixte Biotechnology Holdings, Inc. Announces That Enrollment Has Resumed in National Cancer Institute’s Trial to Determine Ability of Lixte Compound Lb-100 to Enter Recurrent,...

[Lixte Biotechnology Holdings, Inc.] Lixte Biotechnology Holdings, Inc. announced that the National Cancer Institute has resumed enrolling patients into their pharmacologic study of the ability of Lixte’s lead compound, LB-100, to enter the brain and penetrate recurrent, malignant brain tumors, in patients where surgical removal of their cancer is indicated.

Protective Activity of mRNA Vaccines against Ancestral and Variant SARS-CoV-2 Strains

[Science Translational Medicine] The authors assessed the immunogenicity and protective activity of historical or modified Moderna mRNA vaccines in 129S2 and K18-hACE2 mice.

Integrated Immunovirological Profiling Validates Plasma SARS-CoV-2 RNA as an Early Predictor of COVID-19 Mortality

[Science Advances] To identify early predictors of mortality within 60 days of symptom onset, researchers performed immunovirological assessments on plasma from 279 individuals.

A Single Dose, BCG-Adjuvanted COVID-19 Vaccine Provides Sterilising Immunity against SARS-CoV-2 Infection

[NPJ Vaccines] Scientists exploited the immunostimulatory properties of bacille Calmette-Guérin, the existing tuberculosis vaccine, to deliver a vaccination regimen with potent SARS-CoV-2-specific protective immunity.

Dual Electrochemical Sensing of Spiked Virus and SARS-CoV-2 Using Natural Bed-Receptor (MV-gal1)

[Scientific Reports] Investigators introduced a natural bed-receptor surface as Microparticle Vesicle-Galactins1 (MV-gal1) with the ability of glycan binding to screen every spiked virus.

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