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COVID-19

Enhanced Protective Immunity against SARS-CoV-2 Elicited by a VSV Vector Expressing a Chimeric Spike Protein

[Signal Transduction and Targeted Therapy] Using wild-type and human ACE2 knock-in mouse models, investigators found a single dose of rVSV-SARS-CoV could elicit strong humoral immune response via both intranasal and intramuscular routes.

Direct SARS-CoV-2 Infection of the Human Inner Ear May Underlie COVID-19-Associated Audiovestibular Dysfunction

[Communications Medicine] The authors reported a series of ten COVID-19 patients with audiovestibular symptoms such as hearing loss, vestibular dysfunction and tinnitus.

Stem Cell-Based Therapy for COVID-19 and ARDS: A Systematic Review

[NPJ Regenerative Medicine] Scientists performed a systematic review of clinical studies investigating different types of stem cells as treatments for COVID-19 and ARDS to evaluate the safety and potential efficacy of cell therapy.

Immunogenic and Efficacious SARS-CoV-2 Vaccine Based on Resistin-Trimerized Spike Antigen SmT1 and SLA Archaeosome Adjuvant

[Scientific Reports] Researchers evaluated novel protein subunit vaccine formulations containing a resistin-trimerized spike antigen, SmT1.

Pfizer and BioNTech Receive First U.S. FDA Emergency Use Authorization of a COVID-19 Vaccine in Children Ages 5 Through 11 Years

[Pfizer, Inc.] Pfizer, Inc. and BioNTech SE announced that the FDA has authorized for emergency use the Pfizer-BioNTech COVID-19 Vaccine for children 5 through 11 years of age.

Vitti Labs Announces FDA Approval of IND Application for Phase II Clinical Trial of Combination Mesenchymal Stem Cell and Exosome Treatment of Novel Corona...

[Vitti Labs (PR Newswire, Inc.)] Vitti Labs announced that the US FDA has approved its Investigational New Drug (IND) application to conduct Phase II Clinical Trials using a combination of umbilical cord mesenchymal stem cell and umbilical cord mesenchymal stem cell exosomes for the treatment of Acute Respiratory Distress Syndrome associated with COVID-19.

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