cyclin D1

[Scientific Reports] Scientists clarified the role and mechanisms of action of apoptosis-associated speck-like protein containing a caspase recruitment domain in pancreatic ductal adenocarcinoma using clinical evidence and in vitro data.

[Cell Death Discovery] The authors demonstrated that MMP1 derived from tumor-associated macrophages markedly facilitated colon cancer cell proliferation via accelerating cell cycle transition from G0/G1 to S and G2/M phase.

[Arteriosclerosis Thrombosis and Vascular Biology] Researchers investigated the role and mechanism of circSOD2 in smooth muscle cell proliferation and neointima formation.

[Molecular Medicine Reports] Scientists investigated the specific mechanism underlying the effects of miR‑532‑5p on diabetes. Cell viability was determined using an MTT assay. The expression levels of miR‑532‑5P, cyclin D1, Insulin1 and Insulin2 were detected using reverse transcription‑quantitative PCR.

[Biomedicine & Pharmacotherapy] Anti-carcinogenic properties of amorphous curcumin, a compound with improved solubility and bioavailability, were evaluated against human colorectal cancer organoids.

[Naunyn-Schmiedebergs Archives of Pharmacology] HepG2 and Huh7 cells were treated with different concentrations of L-leucine, L-glutamine, or L-methionine and cell viability was determined using MTT assay. Insulin-like growth factor 1, phosphorylated ribosomal protein S6 kinase, p53, and cyclin D1 protein levels were assayed using ELISA.