dendritic cells

[EMBO Journal] Via targeted deletion of virus-recognition innate immune pathways, scientists identified TLR7-MyD88 signaling as crucial for production of antiviral interferons, whereas TLR2 is responsible for the inflammatory IL-6 response.

[Scientific Reports] Gene expression was measured in mice receiving no immunotherapy; and in which anaphylaxis could never occur.

[Advanced Materials] Researchers investigated the immunological effect of chiral nanomaterials as therapeutic and preventive options against tumors.

[Scientific Reports] Evaluations using human MSCs showed that pure polylactic acid (PLA) scaffolds exerted an osteoconductive effect, whereas PLA/hydroxyapatite scaffolds efficiently induced osteogenic differentiation of MSCs even in the absence of any classical osteogenic stimuli.

[Heliyon] This model consisted of a co-culture of Caco-2 and HT29-MTX-E12 cells grown on a semi-wet interface with mechanical stimulation to represent the mucus layer.

[Nature Communications] In wild type endothelial cells Lkb1 phosphorylates polypyrimidine tract binding protein 1 at threonine 138, which regulated stem cell factor pre-mRNA splicing.