diabetic nephropathy

[Life Sciences] The aim of this review is to summarize and provide an overview of the role of swiprosin-1 in pathophysiological conditions of cancers, cardiovascular diseases, diabetic nephropathy, neuropsychiatric diseases, and in the process of inflammation, immune response, and inflammatory diseases.

[Cell Death Discovery] Researchers determined the effect and potential mechanism of Heparanase on glomerular endothelial cells phenotype under high-glucose conditions.

[Respiratory Research] In vivo, intraperitoneal injection of Nifuroxazide relieved and reversed pulmonary fibrosis caused by bleomycin bronchial instillation.

[Gene Therapy] Researchers elucidated that exosomal miR-133b-3p from bone marrow MSCs suppressed angiogenesis and oxidative stress in diabetic retinopathy via FBN1 repression.

[Stem Cell Research & Therapy] In recent years, a growing line of research has shown the participation of exosomal microRNAs in the pathophysiological processes of diabetic nephropathy (DN), which may provide effective therapeutic and biomarker tools for DN treatment.

[Endocrine Journal] Knockdown of potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) suppressed proliferation, ECM accumulation, inflammation, and oxidative stress in high glucose (HG)-cultured human glomerular mesangial cells in vitro.