Tag results:
endothelial cells
Endothelial Cell News
Novel Indolic AMPK Modulators Induce Vasodilatation through Activation of the AMPK–eNOS–NO Pathway
[Scientific Reports] Scientists reported the identification of a novel adenosine monophosphate-activated protein kinase (AMPK) modulator, the indolic derivative IND6, which showed affinity for AMPKα1β1γ1, the primary AMPK isoform in human EA.Hy926 endothelial cells.
Endothelial Cell News
Bone Marrow-Independent Adventitial Macrophage Progenitor Cells Contribute to Angiogenesis
[Cell Death & Disease] Macrophage-derived VEGF activated CD34+ progenitor cells within the adventitial vasculogenic zone to differentiate into CD31+ endothelial cells.
Endothelial Cell News
Integration of Vascular Progenitors into Functional Blood Vessels Represents a Distinct Mechanism of Vascular Growth
[Developmental Cell] Investigators demonstrated that secondary vascular field cells participated in vascular recovery after chemical ablation of vascular endothelial cells.
Hepatic Cell News
Transcriptional Switch of Hepatocytes Initiates Macrophage Recruitment and T Cell Suppression in Endotoxemia
[Journal of Hepatology] Scientists identified a proinflammatory hepatocyte subpopulation that developed primarily from periportal hepatocytes and to a lesser extent from pericentral hepatocytes and played key immunoregulatory roles in endotoxemia.
Mesenchymal Cell News
Increased Phosphatase Regenerating Liver-1 Trigger Vascular Remodeling in Injured Ovary via Platelet-Derived Growth Factor Signaling Pathway
[Stem Cell Research & Therapy] Investigators examined whether by phosphatase regenerating liver-1, overexpressed placental-derived-MSCs, could maximize the angiogenic effects in ovarian tissues injured of a rat model with partial ovariectomy.
Hematopoiesis News
Tet-Mediated DNA Demethylation Regulates Specification of Hematopoietic Stem and Progenitor Cells during Mammalian Embryogenesis
[Science Advances] Scientists found that global or endothelial-specific loss of all three Tet enzymes immediately after gastrulation led to a reduced number of HSCs and progenitor cells and lethality in mid-gestation mouse embryos.