endothelial cells

[Biophysical Journal] Using cultured HUVECs, scientists looked for sites of extracellular vesicle release using ultra-rapid freezing, freeze substitution, and serial section electron microscopy.

[Biophysical Journal] Transient receptor potential vanilloid 4 (TRPV4) enabled endothelial cells, smooth muscle cells, and perivascular neurons, to integrate hemodynamic forces to regulate systemic blood pressure.

[Blood] Scientists observed that endothelial colony forming cells derived from patients with low Von Willebrand Factor (VWF) demonstrated alterations in baseline Weibel Palade body metrics and exhibited impaired VWF release.

[European Heart Journal] The authors investigated the role of valvular endothelial cell-derived tetrahydrobiopterin in aortic valve calcification.

[Nature Cardiovascular Research] Researchers presented the transcriptional response of human cardiomyocytes to pressure overload caused by aortic valve stenosis and described major alterations in cardiac cellular crosstalk.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers described the identification of vimentin, an intermediate filament protein widely expressed in cells of mesenchymal origin, as an important attachment factor for SARS-CoV-2 on human endothelial cells.