Tag results:

endothelial cells

miR-548j-5p Regulates Angiogenesis in Peripheral Artery Disease

[Scientific Reports] The effects of specific miRNAs on angiogenesis were evaluated by assessing the in vitro angiogenic function of endothelial progenitor cells, performing an in vivo angiogenesis assay, and employing a mouse hindlimb ischemic model.

Pre-Configuring Chromatin Architecture with Histone Modifications Guides Hematopoietic Stem Cell Formation in Mouse Embryos

[Nature Communications] The authors performed multi-omics dissection of the hematopoietic stem cell (HSC) ontogeny trajectory across early arterial endothelial cells (ECs), hemogenic ECs, pre-HSCs and long-term HSCs in mouse embryos.

MEG8 Regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) Expression in the Endothelium

[Scientific Reports] Scientists investigated the role of maternally expressed gene 8 (MEG8) specifically in endothelial function as well as the underlying mechanism, hypothesizing that it plays an important role in cardiovascular disease via epigenetic regulation of gene expression.

Liraglutide Prevents High Glucose Induced HUVECs Dysfunction via Inhibition of PINK1/Parkin-Dependent Mitophagy

[Molecular and Cellular Endocrinology] Investigators characterized the potential effects of liraglutide, a glucagon-like peptide-1 receptor agonist, on preventing high glucose-induced endothelial dysfunction and excessive mitophagic response.

Tumors Resurrect an Embryonic Vascular Program to Escape Immunity

[Science Immunology] It is assumed that angiogenesis-induced suppression of adhesion molecules is a regulatory function to provide an embryo with immune privileged conditions and allow uninterrupted growth and development. It is becoming clear that similar conditions are used by tumors to evade the immune system and ensure progressive growth.

Cardiovascular Ramifications of Therapy-Induced Endothelial Cell Senescence in Cancer Survivors

[Biochimica Et Biophysica Acta-Molecular Basis of Disease] The authors discuss the mechanisms of cancer therapy-induced senescence, focusing on endothelial cell senescence since it has been shown to be a key player in numerous cardiovascular complications.

Popular