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endothelial cells

Nanoparticles Functionalized with Stem Cell Secretome and CXCR4-Overexpressing Endothelial Membrane for Targeted Osteoporosis Therapy

[Journal of Nanobiotechnology] Researchers fabricated nanoparticles (NPs) using polylactic-co-glycolic acid loaded with the secretome (Sec) from MSCs to form MSC-Sec NPs.

Endometrial Stromal Cell Ferroptosis Promotes Angiogenesis in Endometriosis

[Cell Death Discovery] Scientists revealed that endometrial stromal cell ferroptosis in the ovarian endometrioma may have triggered cytokine secretion and promoted angiogenesis of adjacent lesions via paracrine actions to drive the development of endometriosis.

Single-Cell Architecture and Functional Requirement of Alternative Splicing during Hematopoietic Stem Cell Formation

[Science Advances] Investigators used single-cell full-length transcriptome data to construct an isoform-based transcriptional atlas of the murine endothelial-to-HSC transition, which enabled the identification of hemogenic signature isoforms and stage-specific alternative splicing events.

The Landscape of Human Tissue and Cell Type Specific Expression and Co-Regulation of Senescence Genes

[Molecular Neurodegeneration] The authors performed an integrative gene network analysis of bulk and single-cell RNA-seq data in non-diseased human tissues to investigate senescence gene co-expression signatures and their cell-type specificity.

Endothelial-Derived Extracellular microRNA-92a Promotes Arterial Stiffness by Regulating Phenotype Changes of Vascular Smooth Muscle Cells

[Scientific Reports] The authors investigated the role of endothelial-derived extracellular microRNA-92a in promoting arterial stiffness by regulating endothelial cell–vascular smooth muscle cell communication.

Endothelial Cells Are an Important Source of BDNF in Rat Skeletal Muscle

[Scientific Reports] Scientists provided a comprehensive analysis of BDNF localization in rat skeletal muscle.

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