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endothelial cells

Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers

[Molecular Cancer Research] Hypoxia increased androgen receptor expression and transcriptional activity in prostate cells in vitro.

Mechanical Control of Innate Immune Responses against Viral Infection Revealed in a Human Lung Alveolus Chip

[Nature Communications] Researchers used a human lung alveolus chip that experienced cyclic breathing-like deformations to investigate whether physical forces influenced innate immune responses to viral infection.

3D Patient-Derived Tumor Models to Recapitulate Pediatric Brain Tumors In Vitro

[Translational Oncology] Scientists adapted a previously established brain tissue-model to fresh patient tumor cells with the goal of establishing 3D in vitro culture conditions for each tumor type.

Therapeutic Correction of Hemophilia A by Transplantation of hPSC-Derived Liver Sinusoidal Endothelial Cell Progenitors

[Cell Reports] The authors developed an efficient and scalable protocol to produce human pluripotent stem cell-derived liver sinusoidal endothelial cells progenitors characterized as venous endothelial cells from different mesoderm subpopulations.

Specification of Fetal Liver Endothelial Progenitors to Functional Zonated Adult Sinusoids Requires C-maf Induction

[Cell Stem Cell] Scientists studied heterogeneity of hepatic vascular cells during mouse development through functional and single-cell RNA-sequencing.

Cardioprotective Effect of Extracellular Vesicles Derived from Ticagrelor-Pretreated Cardiomyocyte on Hyperglycemic Cardiomyocytes through Alleviation of Oxidative and Endoplasmic Reticulum Stress

[Scientific Reports] Scientists investigated the anti-oxidative and cardioprotective effect of extracellular vesicles derived from ticagrelor-pretreated cardiomyocytes under diabetes mellitus conditions.

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