endothelial cells

[Nature Communications] Investigators showed that SHP2 was activated in tumor endothelia. Shp2 deletion and pharmacological inhibition reduced tumor growth and microvascular density in multiple mouse tumor models.

[Haematologica] Researchers reviewed the numerous studies performed during the last decade identifying endothelial cell dysregulation as a factor contributing to myeloproliferative neoplasms disease development.

[Scientific Reports] Investigators reported a role for excessive neutrophil extracellular trap formation induced by uremic serum on endothelial cell injury.

[Tissue Engineering Part C-Methods] The authors described an effective method of isolating a human placenta substrate that induced the spontaneous formation of an interconnected network of green fluorescence labeled HUVECs in vitro.

[Autophagy] Researchers identified endothelial cell autophagy as a negative regulator of neutrophil diapedesis in acute physiological inflammation.

[Journal of Diabetes Research] Scientists prepared and identified endothelial progenitor cells (EPCs), and the biological functions and molecular characteristics were compared between EPCs from DB/+ and DB/DB mice.