Tag results:
endothelial cells
Endothelial Cell News
Aging-Induced Impaired Endothelial Wall Shear Stress Mechanosensing Causes Arterial Remodeling via JAM-A/F11R Shedding by ADAM17
[GeroScience] The authors determined the novel role for a disintegrin and metalloproteinase 17 in impaired wall shear stress mechanosensing, which was hypothesized to contribute to aging-associated abnormal vascular remodeling.
Endothelial Cell News
Dysregulation of the miR-30a/BiP Axis by Cigarette Smoking Accelerates Oral Cancer Progression
[Cancer Cell International] The effects of conditioned media from oral squamous cell carcinoma cells on the angiogenic activities of endothelial cells were analyzed using a tube formation assay.
Immune Regulation News
Stabilin Receptors Clear LPS and Control Systemic Inflammation
[iScience] Scientists discovered that lipopolysaccharide clearance through liver sinusoidal endothelial cells involves endocytosis and lysosomal inactivation via Stabilin-1 and 2 but doesn’t involve TLR4.
Endothelial Cell News
Fraxinellone Ameliorates Intracerebral Hemorrhage-Induced Secondary Brain Injury by Regulating Krüppel-Like Transcription Factor 2 Expression in Rats
[Brain Research Bulletin] An intracerebral hemorrhage (ICH) model was established by injecting autologous blood into the right basal ganglia of Sprague-Dawley rats. After ICH induction, the protein levels of Krüppel-like transcription factor 2 were reduced.
Hepatic Cell News
Single-Cell RNA Transcriptome Landscape of Hepatocytes and Non-Parenchymal Cells in Healthy and NAFLD Mouse Liver
[iScience] To obtain a cellular resolution of pathogenesis, 82,168 single-cell transcriptomes across different nonalcoholic fatty liver disease stages were profiled, identifying hepatocytes and 12 other non-parenchymal cell types.
Endothelial Cell News
miR548ai Antagonism Attenuates Exosome-Induced Endothelial Cell Dysfunction
[Cell Death Discovery] Investigators suggested that miR548ai, a rarely known microRNA, may have provided a molecular target for protection against smooth muscle cell/exosome-induced endothelial cell dysfunction.