endothelial cells

[Signal Transduction and Targeted Therapy] In vitro results showed that MSC-small extracellular vesicles reduced senescent biomarkers, decreased senescence-associated secretory phenotype, rescued angiogenesis, migration and other dysfunctions in senescent endothelial cell induced by oxidative stress.

[Nature Neuroscience] In brains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals and animal models, scientists found an increased number of empty basement membrane tubes, so-called string vessels representing remnants of lost capillaries.

[Scientific Reports] Researchers investigated whether electroporation-mediated gene transfer of MRCKα to the lungs can attenuate LPS-induced acute lung injury in vivo.

[Translational Psychiatry] Scientists found that bilobalide inhibited Aβ-induced and STAT3-dependent expression of TNF-α, IL-1β, and IL-6 in primary astrocyte culture.

[Journal of Molecular and Cellular Cardiology] Scientists checked transcriptional profile by microarray and found Hippo pathway was changed and the activity of YAP decreased during mesoderm-mediated endothelial cell differentiation from human ESCs.

[iScience] Investigators optimized the in vitro liver fibrotic niches and subsequently harvested their bioactive ingredients as niche extracts