endothelial cells

[Science Translational Medicine] Investigators used multiomics analysis of human cirrhotic liver, a Western diet – and carbon tetrachloride – induced minipig nonalcoholic steatohepatitis model, and genetically modified mice to unravel the landscape of the vascular adaptome at the single-cell level, in which endothelial cells and TH17 cells jointly contributed to liver cirrhosis.

[Communications Biology] Researchers reported a method for seeding and engrafting primary porcine hepatocytes into a bioengineered liver scaffold previously reendothelialized with human umbilical vein endothelial cells.

[Circulation Research] HUVECs were exposed to either laminar flow or oscillating disturbed flow for 24 hours in a cone-and-plate device.

[Experimental and Molecular Medicine] Scientists employed MHY-1685, a novel mammalian target of rapamycin inhibitor, and examined its long-term priming effect on the activities of senile human cardiac stem cells (hCSCs) and the functional benefits of primed hCSCs after transplantation.

[Scientific Reports] Scientists reported on an effort to decipher the alignment of brain microvasculature endothelial cells to physical constrains generated via adhesion control on hydrogel surfaces and explored the corresponding responses upon glucose level variations emulating the hypo- and hyperglycaemic effects in diabetes.

[Redox Biology] The authors analyzed key parameters of endothelial function after exposure to aqueous smoke extracts of a heated tobacco product, an electronic cigarette, a conventional cigarette and pure nicotine.