endothelial cells

[Pharmacological Research] The authors showed that the number of endothelial progenitor cells (EPCs) in hypertensive patients was significantly lower than that of normal population, and the cell function decreased with a higher proportion of EPCs at later stages.

[Experimental Cell Research] Researchers examined the involvement of advanced glycation end (AGE)-related receptors on AGE-induced angiogenesis in endothelial cells.

[Vascular Pharmacology] Investigators assessed the therapeutic potential of dihydroceramide desaturase 1 inhibition, the last enzyme involved in de novo ceramide synthesis, to mitigate the vascular effects of the protein-bound uremic toxins indoxyl sulfate

[Journal of Cardiovascular Pharmacology] Researchers found that NAMPT overexpression protected human coronary artery endothelial cells from H2O2-induced injury through promoting cell viability, inhibiting cell apoptosis, enhancing cell motility, and promoting tube formation.

[Inflammation] The authors investigated the effect of crosstalk between retinal pigment epithelial (RPE) cells and choroidal endothelial cells via the ANXA1/FPR2/NLRP3 inflammasome/pyroptosis axis on the development of choroidal neovascularization in vitro and in vivo.

[Journal of Cardiovascular Translational Research] The proangiogenic effect of bovine milk exosomes was analyzed both in isoproterenol-induced cardiac fibrosis rats in vivo and in HUVECs after oxygen and glucose deprivation in vitro.