endothelial cells

[Advanced Drug Delivery Reviews] Reseachers overview recent findings from human study and animal models on the pathophysiological communication among hepatocytes, Kupffer cells, hepatic stellate cells and liver sinusoidal endothelial cells during the disease development.

[Scientific Reports] Researchers characterized primary FVIII-producing organ and cell species using genetically engineered mice, in which enhanced green fluorescent protein was expressed instead of the F8 gene.

[Nature Communications] SNO-GNAI2 acted by coupling with CXCR5 to dephosphorylate the Hippo pathway kinase LATS1, thereby leading to nuclear translocation of YAP and promoting an inflammatory response in endothelial cells.

[JCI Insight] Scientists found that L-SIGN was highly expressed on human liver sinusoidal endothelial cells and lymph node lymphatic endothelial cells but not on blood endothelial cells.

[Anti-Cancer Agents in Medicinal Chemistry] The authors identified five candidate genes, including ESM1，CXCR4，JAG1，FLT1 and PTK2 and two pathways, including Rap1 signaling pathway and PI3K-Akt signaling pathway in vascular endothelial cells that differentiate into tip cells and stalk cells using bioinformatic analysis.

[Cell Biology International] Cardiac function, myocardial infarction area, apoptosis, and angiogenesis were all evaluated in a CHF rat model following treatment with human umbilical cord MSC-derived exosomes.