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endothelial cells

Canagliflozin Protects against Sepsis Capillary Leak Syndrome by Activating Endothelial α1AMPK

[Scientific Reports] Scientists report that canagliflozin, used at clinically relevant concentrations, counteracts lipopolysaccharide-induced vascular hyperpermeability and albumin leakage in wild-type, but not in endothelial-specific α1AMPK-knockout mice.

Spatial Transcriptome Profiling by MERFISH Reveals Fetal Liver Hematopoietic Stem Cell Niche Architecture

[Cell Discovery] Scientists investigated the spatial organization and transcriptional profile of individual HSCs in both wild type and Tet2−/− fetal livers, by multiplexed error robust fluorescence in situ hybridization.

Ultrasonic Microbubble VEGF Gene Delivery Improves Angiogenesis of Senescent Endothelial Progenitor Cells

[Scientific Reports] In the ultrasonic microbubble transfection groups, higher pDNA-derived protein expression was found in senescent endothelial progenitor cells (EPCs) than in young EPCs.

Dual Role of WNT5A in Promoting Endothelial Differentiation of Glioma Stem Cells and Angiogenesis of Glioma Derived Endothelial Cells

[Oncogene] Researchers reported that wingless-related integration site family member 5A (WNT5A) played significant roles in glioma stem cell endothelial differentiation and glioma-derived endothelial cells' angiogenesis.

High Stretch Induces Endothelial Dysfunction Accompanied by Oxidative Stress and Actin Remodeling in Human Saphenous Vein Endothelial Cells

[Scientific Reports] Investigators tested the hypothesis that high stretch (HS) induces human saphenous vein endothelial cell dysfunction and examined candidate underlying mechanisms.

Th17/IL-17 Induces Endothelial Cell Senescence via Activation of NF-κB/p53/RB Signaling Pathway

[Laboratory Investigation] The proportion of Th17 cells in the spleen and the expression levels of IL-17A, IL-6, and vascular cell adhesion molecule- in mice of different ages were increased with aging.

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