enterocytes

[Molecular Nutrition & Food Research] The authors suggested that KFP-1, a novel calcium-binding peptide, bound extracellular calcium ions and entered Caco-2 and IEC-6 cells, and promoted calcium uptake through TRPV6 calcium channels.

[International Journal of Molecular Sciences] The authors summarize recent advances in the field of bile acid signaling, studies of inflamed gut microbiome, and the therapeutic potential of bile acids in the context of inflammatory bowel disease.

[Developmental Cell] Using a Drosophila intestinal model, scientists found that tumor cells outcompeted nearby enterocytes by influencing cell adhesion and contractility.

[Cancer Research] The authors determined that 14-3-3σ expression was significantly downregulated in primary human colorectal cancer when compared with adjacent normal colonic tissue in patient samples. Downregulation of 14-3-3σ in primary colorectal cancers was significantly associated with p53 mutation, increasing tumor stage, distant metastasis, and poor patient survival.

[Cell Death & Disease] Neutrophil extracellular traps treatment induced intestinal epithelial monolayer barrier disruption and endoplasmic reticulum (ER) stress activation in a dose-dependent manner in vitro, and ER stress inhibition markedly attenuated intestinal apoptosis and tight junction injury.

[Nature Communications] Investigators showed that the intestine-enriched miR-802 was a central regulator of intestinal epithelial cell proliferation, Paneth cell function, and enterocyte differentiation.