epithelial cells

[Scientific Reports] Scientists described a complete screening process combining in vitro and in vivo assays to conduct a rational selection of a live strain of Christensenella minuta with strong immunomodulatory properties.

[Cell Reports] Researchers identified five Clostridium strains that suppressed immune-mediated NF-κB activation in epithelial cell lines, peripheral blood mononuclear cells, and gut epithelial organoids from healthy human subjects and patients with inflammatory bowel disease.

[Matrix Biology] To identify the integrin adhesion systems that operate in PDAC, investigators analyzed a range of pancreatic ductal epithelial cell models using 2D, 3D and organoid culture systems.

[Environmental Toxicology] Researchers investigated the effects of glyphosate-based herbicides on antioxidant capacity, inflammatory cytokines, and autophagy of porcine intestinal epithelial cells IPEC-J2 and its molecular mechanism.

[Nature Communications] Investigators showed that the aryl hydrocarbon receptor was important for the termination of the regenerative response and the reacquisition of mature epithelial cell identity post injury in vivo and in organoid cultures in vitro.

[Cancer Gene Therapy] In primary prostate luminal epithelial cells, following inducible oncogenic Kras expression or Pten depletion, TMPRSS2-ERG suppressed oncogene-induced senescence, independent of TP53 induction and RB1 inhibition.