Extracellular Matrix News

[Frontiers in Immunology] Investigators cover the contribution of FcγRs to antigen-presentation with a focus on the intracellular trafficking of IgG-immune complexes and the pathways that support this function.

[Embo Journal] Investigators showed that glioblastoma (GBM)‐initiating cells induced mTOR signaling in the microglia but not bone marrow‐derived macrophages in both in vitro and in vivo GBM mouse models.

[Journal of Immunology] lncRNA interactome, RNA immunoprecipitation, and coimmunoprecipitation studies identified BCR-mediated Ca+ signaling (BCALM)-interacting proteins in B cells, including phospholipase D 1, and kinase adaptor proteins AKAP9 and AKAP13.

[Arthritis Research & Therapy] The authors identified the molecular mechanism of dysregulation of B cell subpopulations of primary Sjögren’s syndrome at the transcriptome level.

[Circulation Research] Direct co-culture with postnatal cardiac fibroblasts increased cardiomyocyte binucleation, which could be inhibited by RGD peptide treatment.

[European Journal of Human Genetics] Researchers investigated the anti-fibrotic activity of a flowable placental formulation using a bleomycin-induced dermal fibrosis model in aged mice.