extracellular matrix

[Cell Death Discovery] Researchers used a library containing approved drugs to screen for drugs that preferentially reduce cell viability in lung fibroblasts from an IPF patient compared with a human alveolar epithelial cell line.

[Advanced Healthcare Materials] Researchers used a recently developed composite hydrogel composed of a fibrin matrix and phase-shift emulsion, termed an acoustically-responsive scaffold, to investigate effects of local mechanical properties on breast cancer cell signaling.

[Cell Death Discovery] Investigators showed that circ_0134111 level was overexpressed in intervertebral disc degeneration (IDD) tissue samples as compared to control tissues. The upregulation of circ_0134111 was more drastic in the moderate and severe IDD cases than in those with mild IDD.

[Small] Scientists introduce the classification, design, and assembly of DNA hydrogels, and then summarize the state-of-the-art achievements in cell encapsulation, cell culture, and tissue engineering with DNA hydrogels.

[British Journal of Cancer] The authors explain the process of ECM stiffening and the ways it may affect biochemical pathways to induce chemoresistance in a clinic.

[Scientific Reports] Researchers investigated the impact of CD26 deficiency in human primary fibroblasts on the regeneration of human tissue-engineered skin substitutes in vivo.