Tag results:

extracellular matrix

Integrins Regulate Stemness in Solid Tumor: An Emerging Therapeutic Target

[Journal of Hematology & Oncology] Scientists discuss the integrin signalosome with a highlight of a few key pro-oncogenic pathways elicited by integrins, and uncover the mutational and transcriptomic landscape of integrin-encoding genes across human cancers.

Cardiac Aorta-Derived Extracellular Matrix Scaffold Enhances Critical Mediators of Angiogenesis in Isoproterenol-Induced Myocardial Infarction Mice

[Journal of Materials Science-Materials in Medicine] The authors investigated whether cardiomyocytes culturing on cardiac aorta-derived extracellular matrix scaffold had advantageous effects on cardiomyocytes survival and angiogenesis biomarkers’ expression.

The Role of Vascular Smooth Muscle Cells in the Development of Aortic Aneurysms and Dissections

[European Journal of Clinical Investigation] The authors summarize current knowledge about vascular smooth muscle cells (vSMCs) functions within the aortic wall and give an overview of how vSMC functions are dysregulated in aortic aneurysms and aortic dissections pathogenesis, organized per anatomical location.

Novel Human Placenta-Based Extract for Vascularization Strategies in Tissue Engineering

[Tissue Engineering Part C-Methods] The authors described an effective method of isolating a human placenta substrate that induced the spontaneous formation of an interconnected network of green fluorescence labeled HUVECs in vitro.

Human Liver Stem Cell Transplantation Alleviates Liver Fibrosis in a Rat Model of CCl4-Induced Liver Fibrosis

[International Journal of Stem Cells] Investigators introduced a rat model of liver fibrosis and trans-portal transplantation of human liver stem cells to demonstrate alleviation of liver fibrosis.

Coordination of Fungal Biofilm Development by Extracellular Vesicle Cargo

[Nature Communications] Researchers defined functions for numerous extracellular vesicle cargo proteins in biofilm matrix assembly and drug resistance, as well as in fungal cell adhesion and dissemination.

Popular