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fibronectin
Mesenchymal Cell News
Mucin 5AC-Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate Pancreatic Cancer Stromal Heterogeneity
[Gastroenterology] Autochthonous murine models of pancreatic cancer (PC) and co-implanted allografts of murine PC cell lines with adipose-derived MSCs were used to assess the role of Muc5ac in stromal heterogeneity.
Extracellular Matrix News
PD-L1 Mediates Lung Fibroblast to Myofibroblast Transition through Smad3 and β-Catenin Signaling Pathways
[Scientific Reports] Researchers demonstrated that fibroblast programmed death ligand-1 (PD-L1) may have promoted pulmonary fibrosis through both Smad3 and β-catenin signaling and may represent a novel interventional target for idiopathic pulmonary fibrosis.
Hepatic Cell News
PD-L1 Blockade Liberates Intrinsic Antitumourigenic Properties of Glycolytic Macrophages in Hepatocellular Carcinoma
[Gut] Scientists elucidated the nature, regulation and functional relevance of PD-L1+ host cells in HCC.
Extracellular Matrix News
Proteomic Profile of Extracellular Matrix from Native and Decellularized Chorionic Canine Placenta
[Journal of Proteomics] The authors studied the proteome profiled of canine native and decellularized placenta to characterize the proteome related to maintenance of a microenvironment and structure suitable for tissue engineering applications.
Umbilical & Placental Cell News
Introduction of an Efficient Method for Placenta Decellularization with High Potential to Preserve Ultrastructure and Support Cell Attachment
[Artificial Organs] Human placenta was decellularized by four protocols and decellularization efficacy was compared by hematoxylin and eosin, 4′,6-diamidino-2-phenylindole staining, and DNA measurement.
Extracellular Matrix News
Caveolin-1 Alleviates Crohn’s Disease–Induced Intestinal Fibrosis by Inhibiting Fibroblasts Autophagy through Modulating Sequestosome 1
[Inflammatory Bowel Diseases] Human Crohn's disease (CD) tissue samples were gained from patients with CD who underwent surgical resection of the intestine and were defined as stenotic or nonstenotic areas.