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flow cytometry

Single-Cell Analysis of Skin Immune Cells Reveals an Angptl4-ifi20b Axis That Regulates Monocyte Differentiation during Wound Healing

[Cell Death & Disease] The authors performed flow cytometry and single-cell RNA sequencing to examine the immune cell landscape of excisional wounds from Angptl4+/+ and Angptl4−/− mice.

MiR-29b-3p Inhibits the Inflammation Injury in Human Umbilical Vein Endothelial Cells by Regulating SEC23A

[Biochemical Genetics] The authors investigated the effects of miR-29b-3p on the inflammation injury of HUVECs induced by lipopolysaccharide and explored the underlying mechanisms.

Tacrolimus-Resistant SARS-CoV-2-Specific T Cell Products to Prevent and Treat Severe COVID-19 in Immunosuppressed Patients

[Molecular Therapy-Methods & Clinical Development] Scientists proposed adoptive transfer of SARS-CoV-2-specific T cells made resistant to a common immunosuppressant, Tacrolimus, for optimized performance in the immunosuppressed patient.

In Vitro and In Vivo Functions of T Cells Produced in Complemented Thymi of Chimeric Mice Generated by Blastocyst Complementation

[Scientific Reports] Researchers generated thymus-complemented chimeric mice, assessed the efficacy of anti-PD-L1 antibody in tumor-bearing chimeric mice, and then investigated T cell function.

Thymic Stromal Lymphopoietin Controls Hair Growth

[Stem Cell Reports] The authors demonstrated that thymic stromal lymphopoietin was produced in response to skin injury and during the anagen phase of the hair cycle.

Mucin 5AC-Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate Pancreatic Cancer Stromal Heterogeneity

[Gastroenterology] Autochthonous murine models of pancreatic cancer (PC) and co-implanted allografts of murine PC cell lines with adipose-derived MSCs were used to assess the role of Muc5ac in stromal heterogeneity.

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