flow cytometry

[Leukemia] Hodgkin lymphoma patients showed a decreased CD4 T-cell fraction, a higher percentage of effector-memory T cells and higher expression of activation markers at baseline.

[Blood Advances] Investigators conducted a multicenter, open-label, Phase II, single-arm study of pembrolizumab in patients with DIPSS intermediate 2 or greater primary, post-essential thrombocythemia or post-polycythemia vera myelofibrosis that were ineligible for or were previously treated with ruxolitinib.

[Journal of Hematology & Oncology] SIRPα-αCD123 antibodies were generated by fusing the extracellular domain of SIRPα to an αCD123 antibody. The binding properties of the antibodies were analyzed by flow cytometry and surface plasmon resonance.

[Surgery] Validated papillary, follicular, and anaplastic human thyroid cancer cell lines in culture were first assessed for autophagic capacity after bafilomycin clamping.

[Medical Oncology] Using orthogonal flow cytometry analysis, scientists demonstrated that primary patient-derived cancer organoid maintain distinct subsets of epithelial cells throughout culture and that these cells conserve expression of androgen receptor-related elements.

[Scientific Reports] Aptamers were selected against acute myeloid leukemia cells expressing the MLL-AF9 oncogene through systematic evolution of ligands by exponential enrichment (SELEX). Twelve rounds of SELEX, including two counter selections against fibroblast cells, were completed.