flow cytometry

[Toxicology and Applied Pharmacology] Investigators modified sets of lipids conjugated with cell-penetrating TAT peptide, MMP2 enzyme-sensitive moiety, and cetuximab antibodies against the EGF receptor were synthesized, purified and verified on HPLC, TLC, SEM, and DLS analyses.

[Stem Cell Research & Therapy] In a wound healing mouse model, the histological evaluation of wound tissue in PBS, bone marrow MSCs (BMSCs), and ascorbic acid 2-glucoside-treated BMSCs group were investigated.

[Molecular Medicine Reports] The authors investigated the role of sigma‑1 receptor (Sig-1R) in islet β‑cell proliferation and examined the effects of Sig‑1R on islet β‑cell injury under lipotoxic conditions.

[PLoS One] Scientists conducted a single center observational cohort study of patients diagnosed with intermittent claudication. Blood and urine samples were collected at rest and following a standardized treadmill exercise protocol.

[Journal of Hematology & Oncology] Investigator established a target-redirected universal CAR-T cell therapeutic modality, in which exogenous antigens were loaded onto fusogenic nanoparticles to achieve in situ modification of cell membrane in solid tumors, providing targets for subsequent CAR-T cell therapy.

[Clinical Cancer Research] Tumor and blood samples were analyzed by flow cytometry, immunohistochemistry, transcriptome and cytokine profiling. Cabozantinib-related effects were validated in a colorectal cancer PDX model.