gastric cancer

[Cell Biology and Toxicology] Scientists explored the role of mesenchymal stem cells (MSC)-derived extracellular vesicles-derived miR-301b-3p in multidrug resistance of gastric cancer cells.

[Cell Death Discovery] Blocking large tumor suppressor kinases 1/2 led to the loss of F-box and WD repeat domain-containing 5 (FBXW5)-mediated regulation of the Hippo pathway and partial functions.

[Cellular and Molecular Life Sciences] The in vitro and in vivo results indicated that CD133+ stem cell-like cells are the main subpopulation and PARP1 was the central gene mediating oxaliplatin resistance in gastric cancer.

[Stem Cells International] Researchers explored whether Mesenchymal stem cell- (MSC-) derived extracellular vesicles-delivered lipocalin-type prostaglandin D2 synthase (L-PGDS) could inhibit gastric cancer progression.

[Cell Death & Disease] NR2F1-AS1 and NR2F1 were highly co-expressed in pan-tissues and pan-cancers. Depletion of NR2F1-AS1 compromised the expression level of NR2F1 in gastric cancer cells.

[Cell Death & Disease] Scientists demonstrated that FTO, a key demethylase for RNA m6A modification, was up-regulated in gastric cancer tissues, especially in tissues with liver metastasis.