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gastric cancer

Emerging Roles of CD133 in the Treatment of Gastric Cancer, a Novel Stem Cell Biomarker and Beyond

[Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences] Scientists summarize the current knowledge of the role of CD133 expression in gastic cancer and aim to contribute at identifying promising new strategies for treatment and management of gastric cancer.

EDDM3A Drives Gastric Cancer Progression by Promoting HIF-1α-Dependent Aerobic Glycolysis

[Oncogenesis] Researchers showed that the expression of EDDM3A was significantly upregulated in gastric cancer tissues and its upregulation correlates with poorer survival in patients with gastric cancer.

AMIGO2 Contained in Cancer Cell-Derived Extracellular Vesicles Enhances the Adhesion of Liver Endothelial Cells to Cancer Cells

[Scientific Reports] Scientists explored the role of cancer cell-derived amphoterin-induced gene and open reading frame 2 (AMIGO2)-containing extracellular vesicles in the adhesion of cancer cells to human hepatic sinusoidal endothelial cells.

Fate Therapeutics Announces FDA Clearance for FT536, a First-in-Class MICA/B-targeted CAR NK Cell Product Candidate for the Treatment of Solid Tumors

[Fate Therapeutics, Inc.] Fate Therapeutics, Inc. announced that the US FDA has cleared the company’s Investigational New Drug application for FT536, an off-the-shelf, multiplexed-engineered, iPSC-derived, chimeric antigen receptor NK cell product candidate.

Transcriptomic Profiling of Single Circulating Tumor Cells Provides Insight into Human Metastatic Gastric Cancer

[Communications Biology] Researchers utilized an antigen-independent strategy for circulating tumor cell (CTC) isolation from metastatic gastric cancer patients involving a size-dependent recovery of CTCs and a single cell isolation technique.

Linc01133 Contributes to Gastric Cancer Growth by Enhancing YES1-Dependent YAP1 Nuclear Translocation via Sponging miR-145-5p

[Cell Death & Disease] Scientists found that linc01133 was significantly upregulated in gastric cancer tissues compared to non-tumorous gastric tissues. Linc01133 over-expression significantly correlated with tumor size and tumor differentiation in gastric cancer patients.

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