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glioblastoma cells

GD2 CAR T Cells against Human Glioblastoma

[npj Precision Oncology] Researchers isolated patient-derived glioblastoma cells showing high GD2 antigen expression representing a potential target for CAR T strategy.

Targeting EYA2 Tyrosine Phosphatase Activity in Glioblastoma Stem Cells Induces Mitotic Catastrophe

[Journal of Experimental Medicine] The authors interrogated gene expression profiles from glioblastoma stem cells, differentiated glioblastoma cells, and neural stem cells, revealing EYA2 as preferentially expressed by GSCs.

The Long Non-Coding RNA HOTAIRM1 Promotes Tumor Aggressiveness and Radiotherapy Resistance in Glioblastoma

[Cell Death & Disease] Scientists identified HOTAIRM1 as a candidate lncRNA whose up-regulation was significantly associated with shorter survival of glioblastoma patients, independent from IDH mutation and MGMT promoter methylation.

Low Temperature Plasma Irradiation Products of Sodium Lactate Solution That Induce Cell Death on U251SP Glioblastoma Cells Were Identified

[Scientific Reports] Scientists quantified several major chemical products, such as pyruvate, formate, and acetate, in plasma-activated L-sodium lactate solution by nuclear magnetic resonance analysis.

The Noncoding RNA LINC00152 Conveys Contradicting Effects in Different Glioblastoma Cells

[Scientific Reports] In search of novel putative therapeutic RNA targets researchers investigated the role of the oncogenic long noncoding RNA LINC00152 in A172 glioblastoma cells.

Identification of Pimavanserin Tartrate as a Potent Ca2+-Calcineurin-NFAT Pathway Inhibitor for Glioblastoma Therapy

[Acta Pharmacologica Sinica] Researchers carried out research to discover a novel alternative drug targeting the oncogenic NFAT signaling pathway for Glioblastoma multiforme therapy.

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