Tag results:

glioblastoma stem cells

Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity

[Cancer Research] Investigators showed that LAMP2A expression was enriched in patient-derived glioblastoma stem cells (GSC), and its depletion diminished GSC-mediated tumorigenic activities.

Canonical WNT Pathway Inhibition Reduces ATP Synthesis Rates in Glioblastoma Stem Cells

[Frontiers in Bioscience-Landmark] Researchers determined live cell metabolism and bioenergetics in pathophysiological relevant, WNT-dependent glioblastoma stem cell models.

Glioblastoma Stem Cells Reprogram Chromatin In Vivo to Generate Selective Therapeutic Dependencies on DPY30 and Phosphodiesterases

[Science Translational Medicine] Scientists identified DPY30, a regulator of histone H3 lysine 4 trimethylation, as a driver of glioblastoma growth in vivo but not in vitro.

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma

[Cancer Research] To investigate recurrently dysregulated genes in glioblastoma, scientists interrogated allele-specific expression, the difference in expression between two alleles of a gene, in glioblastoma stem cells derived from 43 patients.

Targeting Glioblastoma Stem Cells: The First Step of Photodynamic Therapy

[Photodiagnosis and Photodynamic Therapy] Scientists present a brief review exclusively commenting on the therapeutic approaches to eliminate glioblastoma stem cells and on the research publications about this topic of glioblastoma stem cells in relation to photodynamic therapy.

Novel Cancer Stem Cell Marker MVP Enhances Temozolomide-Resistance in Glioblastoma

[Translational Oncology] Researchers found that sensitivity toTemozolomide (TMZ) was suppressed by significantly increasing the major vault protein (MVP) expression in glioblastoma multiforme cells with TMZ resistance.

Popular