Tag results:

glioblastoma

Low Temperature Plasma Irradiation Products of Sodium Lactate Solution That Induce Cell Death on U251SP Glioblastoma Cells Were Identified

[Scientific Reports] Scientists quantified several major chemical products, such as pyruvate, formate, and acetate, in plasma-activated L-sodium lactate solution by nuclear magnetic resonance analysis.

T-Cure Bioscience Announces US FDA Clearance of Investigator-Initiated Clinical Trial for KK-LC-1 TCR-T against Multiple Solid Tumors

[T–Cure Bioscience, Inc.] T–Cure Bioscience, Inc. announced that the US FDA has approved the Investigational New Drug application to initiate a Phase I clinical study evaluating a T cell receptor (TCR)–based product candidate for the treatment of tumors expressing Kita–Kyushu lung cancer antigen 1 (KK-LC-1), such as gastric, cervical, lung, breast cancers and other KK–LC–1 positive epithelial cancers.

Adenosine A2A Receptor Activation Enhances Blood-Tumor Barrier Permeability in a Rodent Glioma Model

[Molecular Cancer Research] Researchers characterized the time-dependent impact of regadenoson on brain endothelial cell interactions and paracellular transport, using mouse and rat brain endothelial cells and tumor models.

circFLNA Promotes Glioblastoma Proliferation and Invasion by Negatively Regulating miR-199-3p Expression

[Molecular Medicine Reports] Researchers aimed to identify differentially expressed circular RNAs in glioblastoma. Reverse transcription‑quantitative PCR was used to analyze the expression levels of circFLNA.

Fenofibrate Inhibits Hypoxia-Inducible Factor-1 Alpha and Carbonic Anhydrase Expression through Activation of AMP-Activated Protein Kinase/HO-1/Sirt1 Pathway in Glioblastoma Cells

[Environmental Toxicology] Researchers studied the regulatory effects of the PPARα agonist fibrate on the regulation of HIF-1α expression and its downstream target protein in glioblastoma.

Viral Targeting of Glioblastoma Stem Cells with Patient-Specific Genetic and Post-Translational p53 Deregulations

[Cell Reports] The authors dissected the genetic and functional heterogeneity of human glioblastoma stem cells within patients by their innate responses to non-pathogenic mouse parvoviruses that were tightly restrained by cellular physiology.

Popular