granulocytes

[British Journal of Anaesthesia] Scientists quantified ex vivo neutrophil extracellular traps (NET) induction in septic humans and murine models of sepsis to identify signalling pathways that may be modulated to improve outcome in human sepsis.

[Scientific Reports] Scientists describe the establishment of primary cocultures of neoplastic mast cells from canine cutaneous mast cell tumors and cancer-associated fibroblasts.

[Journal of Cellular and Molecular Medicine] Researchers developed a 6-gene immune-related risk model to predict the survival of patients with lung adenocarcinoma (LUAD) in The Cancer Genome Atlas cohort based on TP53 status, and the predictive ability was confirmed in two independent cohorts.

[Blood] Intestinal epithelium damage induced the elevated level of alarm cytokine interleukin-33 (IL-33), leading to platelet activation via promoting gut-derived serotonin release.

[Gut] The authors used high-resolution endoscopy and colon tissue samples of active ulcerative colitis as well as experimental models of physical and chemical mucosal damage in mice deficient for peptidyl-arginine deiminase-4, gnotobiotic mice and controls.

[Human Immunology] The authors reviewed the molecular mechanisms and the role of immune cells and responses involved in pulmonary hypertension development.