hematopoietic stem cells

[Haematologica] Researchers reviewed the numerous studies performed during the last decade identifying endothelial cell dysregulation as a factor contributing to myeloproliferative neoplasms disease development.

[Journal of Histochemistry & Cytochemistry] Scientists review recent literature on energy production in glioblastoma stem cells and leukemic stem cells versus their normal counterparts, neural stem cells and hematopoietic stem cells, respectively.

[American Society for Transplantation and Cellular Therapy] Researchers described an umbilical cord blood transplants performed after graft failure following a previous hematopoietic stem cell transplantation.

[Stem Cell Reports] While hematopoietic-specific Cited2 deletion has a minor impact on steady-state hematopoiesis, Cited2-deficient hematopoietic stem cells are severely depleted in young mice and fail to expand upon aging.

[Pharmacogenomics Journal] Scientists explored 51 variants within 17 DNA-repair genes for their association with acute graft versus host disease grades two–four in 60 pediatric patients.

[PLoS One] Brain-derived neurotrophic factor promoted hematopoietic regeneration via activation of PDGFRα+ bone marrow MSCs which increased secretion of hematopoietic cytokines interleukin 6 and leukemia inhibitory factor in response to TrkB activation.