induced pluripotent stem cells

[Kidney International] Kidney organoids may complement animal models for annotating and predicting the molecular and cellular function of these candidate genes.

[Scientific Reports] Researchers conducted a library screening to quantify amyloid β and neuronal toxicity by using cortical neurons from hiPSCs of AD patients after adding secondary metabolites.

[MDimune (EIN Presswire, Inc.)] MDimune announced a joint research agreement with YiPSCELL to develop BioDrone® Platform therapeutics based on iPSCs.

[Nature] Loss of TDP-43 from the nucleus in human brain, neuronal cell lines and motor neurons derived from induced pluripotent stem cells resulted in the inclusion of a cryptic exon in UNC13A mRNA and reduced UNC13A protein expression.

[Cell Reports] Scientists used maturity-onset diabetes of a young 3 patient and CRISPR/Cas9-engineered human induced pluripotent stem cells (hiPSC) grown as 3D organoids to investigate how HNF1αp291fsinsC affected hiPSC differentiation during pancreatic development.

[Scientific Reports] Researchers investigated induced pluripotent stem DCs-in vitro transcriptional RNA (ivtRNA) which were induced by transfecting ivtRNA obtained from tumors of three colorectal cancer patients, and examined its antitumor effect.