influenza

[Cidara Therapeutics, Inc.] Cidara Therapeutics, Inc. announced that the FDA has accepted the company’s Investigational New Drug application for its lead flu drug-Fc conjugate, CD388 – a highly potent, long-acting antiviral immunotherapy designed to deliver universal prevention and treatment of seasonal and pandemic influenza.

[Mucosal Immunology] Most nucleoprotein-specific CD8 T cells in broncho-alveolar lavage and lung are tissue resident memory cells that express CD69 and downregulate CD45RA and CCR7.

[Journal of Virology] Scientists reported the pathogenic and immunological consequences of SARS-CoV-2 and influenza A virus H1N1 coinfection in the K18-hACE2 transgenic mouse model.

[Journal of Food Biochemistry] The literature reported many studies demonstrating that elderberry extract has both antiviral and vascular protective properties that should be further investigated as a nutritional component used against the (in)direct effect of SARS-CoV-2 in vascular function.

[Science Immunology] Scientists characterized tissue-resident memory B cells that were stably maintained in the lungs of mice after pulmonary influenza infection.

[European Respiratory Journal] The authors used a mouse model of concurrent cigarette smoke exposure and H1N1 influenza infection, colony-stimulating factor (CSF)3 supplementation/receptor blockade, and single-cell RNA sequencing to investigate this relationship.