influenza

[Cellular & Molecular Immunology] Investigators reported the immunogenicity and protection induced in rhesus macaques by intramuscular injections of a virus-like particle bearing a SARS-CoV-2 spike protein vaccine candidate formulated with or without Adjuvant System 03 or cytidine-phospho-guanosine 1018.

[Scientific Reports] Researchers reported the design of a multi-epitope vaccine against Hemagglutinin and Neuraminidase proteins of H7N9 Influenza A virus by prediction of Cytotoxic T lymphocyte, Helper T lymphocyte, IFN-γ and B cell epitopes.

[Pfizer, Inc.] Pfizer, Inc. and BioNTech SE announced a new research, development and commercialization collaboration to develop a potential first mRNA-based vaccine for the prevention of shingles.

[NPJ Vaccines] Utilizing multiple influenza antigens, scientists demonstrated the suitability of the mRNA therapeutic platform for such applications.

[Science Immunology] Mouse infant T cells showed increased sensitivity to low antigen doses, originating at the interface between T cells and antigen-bearing accessory cells—through actin-mediated mobilization of signaling molecules to the immune synapse.

[NPJ Vaccines] The authors evaluated pre- and post-vaccination strain-specific hemagglutination inhibition titers in adults over 75 years of age who received a high-dose influenza vaccine in at least four out of six influenza seasons.