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innate lymphoid cells

Hobit Confers Tissue-Dependent Programs to Type 1 Innate Lymphoid Cells

[Proceedings of the National Academy of Sciences of the United States of America] Using Zfp683 reporter mice, scientists showed that correlation of Hobit expression with type 1 innate lymphoid cells was tissue- and context-dependent.

Diversity of Human NK Cell Developmental Pathways Defined by Single-Cell Analyses

[Current Opinion in Immunology] Investigators offer a brief review of new insights into human NK cell diversity specifically defined by next generation sequencing and single-cell transcriptomic studies.

Antigen-Presenting Innate Lymphoid Cells Orchestrate Neuroinflammation

[Nature] Investigators defined a population of inflammatory group 3 innate lymphoid cells that infiltrate the central nervous system in a mouse model of multiple sclerosis.

Establishment of the TBX-Code Reveals Aberrantly Activated T-Box Gene TBX3 in Hodgkin Lymphoma

[PLoS One] Scientists revealed a lymphoid TBX-code and used it to identify an aberrant network around deregulated T-box gene TBX3 in Hodgkin lymphoma which promoted hallmark aberrations of this disease.

ILC3s Control Airway Inflammation by Limiting T Cell Responses to Allergens and Microbes

[Cell Reports] Researchers demonstrated that lymphoid-tissue-inducer-like ILC3s were enriched in the lung-draining lymph nodes of healthy mice and humans.

Innate Immune Defenses at the Maternal-Fetal Interface

[Current Opinion in Immunology] The authors discuss how newly described decidual innate lymphoid cells and maternal placenta-associated macrophage subsets may be involved in anti-pathogen defense.

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