Tag results:

insulin producing cells

A Novel Hybrid Polymer of PCL/Fish Gelatin Nanofibrous Scaffold Improves Proliferation and Differentiation of Wharton’s Jelly-Derived Mesenchymal Cells into Islet-Like Cells

[Artificial Organs] In vitro studies showed, wharton’s jelly-derived-MSCs that differentiated in the 3D culture have strong properties of insulin-producing cells such as islet-like cells.

TAZ Promotes PDX1-Mediated Insulinogenesis

[Cellular and Molecular Life Sciences] Transcriptional co-activator with PDZ-binding motif (TAZ) defect caused structural changes in the pancreas, particularly islet cell shrinkage, and decreased insulin production and β-cell markers expression, leading to hyperglycemia.

MYCL-Mediated Reprogramming Expands Pancreatic Insulin-Producing Cells

[Nature Metabolism] In vitro expression of Mycl provoked active replication in islet cells, even in those from aged mice.

Comparative Analysis of the Therapeutic Effects of Amniotic Membrane and Umbilical Cord Derived Mesenchymal Stem Cells for the Treatment of Type 2 Diabetes

[Stem Cell Reviews and Reports] Researchers compared the therapeutic efficacy of mesenchymal stem cells derived from amniotic membrane and umbilical cord of the same donor in the alleviation of type 2 diabetes mellitus symptoms and explored the underlying mechanisms.

Activation of a Ductal-to-Endocrine Transdifferentiation Transcriptional Program in the Pancreatic Cancer Cell Line PANC-1 Is Controlled by RAC1 and RAC1b through Antagonistic Regulation of...

[Cancers] Researchers showed that inhibition of RAC1 activation attenuated pluripotency marker expression and self-renewal ability, while depletion of RAC1b dramatically enhanced stemness features and clonogenic potential.

Impact of Insulin Producing Cells Derived from Adipose Tissue Mesenchymal Stem Cells on Testicular Dysfunction of Diabetic Rats

[Heliyon] Scientists investigated the effect of insulin-producing cells derived from adipose tissue MSCs on diabetic-induced impairments as the abnormalities of testicular tissues, oxidative stress of testes, and defects of spermatogenesis.