Tag results:
insulin
Pancreatic Cell News
Sodium Butyrate Potentiates Insulin Secretion from Rat Islets at the Expense of Compromised Expression of β Cell Identity Genes
[Cell Death & Disease] Overlapping analysis of H3K27Ac ChIP-seq and RNA-seq showed that the inhibitory effect of SB on the expression of multiple β cell identity genes was independent of H3K27Ac.
Cancer Stem Cell News
FOXP3 Activated-LINC01232 Accelerates the Stemness of Non-Small Cell Lung Carcinoma by Activating TGF-β Signaling Pathway and Recruiting IGF2BP2 to Stabilize TGFBR1
[Experimental Cell Research] Flow cytometry and sphere formation assays indicated that LINC01232 significantly promoted non-small cell lung carcinoma cell stemness.
Pancreatic Cell News
The Idd2 Locus Confers Prominent Resistance to Autoimmune Diabetes
[Journal of Immunology] Researchers generated a NOD congenic mouse bearing B10 resistance alleles on chromosome 9 in a locus coinciding with part of the insulin-dependent diabetes (Idd) locus and found that NOD.
Pulmonary Cell News
Involvement of m6A Regulatory Factor IGF2BP1 in Malignant Transformation of Human Bronchial Epithelial Beas-2B Cells Induced by Tobacco Carcinogen NNK
[Toxicology and Applied Pharmacology] Scientists performed colony formation assays, soft-agar assays, and tumor growth in nude mice to show that 100 mg/L Nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) facilitated the malignant transformation of human bronchial epithelial Beas-2B cells.
Umbilical & Placental Cell News
Comparative Analysis of the Therapeutic Effects of Amniotic Membrane and Umbilical Cord Derived Mesenchymal Stem Cells for the Treatment of Type 2 Diabetes
[Stem Cell Reviews and Reports] Researchers compared the therapeutic efficacy of mesenchymal stem cells derived from amniotic membrane and umbilical cord of the same donor in the alleviation of type 2 diabetes mellitus symptoms and explored the underlying mechanisms.
Mesenchymal Cell News
Using Adipose-Derived Mesenchymal Stem Cells to Fight the Metabolic Complications of Obesity: Where Do We Stand?
[Obesity Reviews] Adipose-derived MSC transplantation may offer a potential therapeutic approach for the treatment of metabolic complications of obesity, but randomized controlled trials are required to establish their safety and efficacy in humans prior to routine clinical use.