insulin

[Cell Death & Disease] Phenotypic and metabolic profiles with associated cellular signaling pathways involved in lipid metabolism were investigated in the mice heart and human cardiomyocytes to establish treatment effect of adiponectin's agonists.

[Journal of Biochemical and Molecular Toxicology] Scientists delineated the role of gymnemic acid in protecting pancreatic β-cells in diabetic animals, with special reference to inflammation and apoptosis.

[Acta Diabetologica] CCK8, Ki67 staining, immunohistochemical analyses, glucose-stimulated insulin secretion and intraperitoneal glucose tolerance test were performed to detect the effect of Kcnq1ot1 on β-cell proliferation and insulin secretion in vitro and in vivo.

[Inflammation Research] Scientists demonstrated the protective role of Insulin-like growth factor 1 (IGF-1) against pancreatic β cell dysfunction and to probe into the underlying mechanisms.

[Food Chemistry] The authors examined the bioactivity of extracts from apple pomace obtained by non-conventional green extraction methods. Bioactivity was antioxidant capacity and ability to stimulate insulin secretion from pancreatic beta-cells.

[Cell Death & Disease] The inhibitory effect of Selenoprotein S (SelS) on hepatic steatosis and insulin resistance was confirmed by SelS overexpression in primary hepatocytes in vitro.